Doxylamine Succinate/Pyridoxine Hydrochloride
نویسندگان
چکیده
منابع مشابه
Doxylamine succinate–pyridoxine hydrochloride (Diclegis) for the management of nausea and vomiting in pregnancy: an overview
Nausea and vomiting in pregnancy (NVP) is common and often undertreated, in part due to fears of adverse effects of medications on the fetus during early pregnancy. In April 2013, the US Food and Drug Administration (FDA) approved doxylamine succinate 10 mg and pyridoxine hydrochloride (a vitamin B6 analog) 10 mg as a delayed-release combination pill called Diclegis for the treatment of NVP. Di...
متن کاملSimultaneous Determination of Doxylamine Succinate, Pyridoxine Hydrochloride and Folic Acid by Chemometric Spectrophotometry
Simultaneous estimation of three component tablets containing Doxylamine succinate (DOX), Pyridoxine hydrochloride (PYR) and Folic acid (FA) was carried out by UV spectrophotometric assisted chemometric methods. Four chemometric methods i.e. classical least square (CLS), inverse least square (ILS), principal component regression (PCR) and partial least squares (PLS) were applied to simultaneous...
متن کاملA Validated Simultaneous Estimation of Doxylamine Succinate and Pyridoxine Hydrochloride by Uv – Spectrophotometric Method in Bulk and Formulation
A simple and rapid UV – Spectrophotometric method was developed and validated for the simultaneous estimation of Doxylamine succinate and Pyridoxine HCl in combined dosage forms. The said combination is used in treating morning sickness associated with pregnancy. For the simultaneous estimation of both drugs, 260 nm and 285 nm were selected as wavelength of analysis. The linearity range was tak...
متن کاملDoxylamine Succinate Overdose: Case Report and Literature Review
Özet Doksilamin süksinat, etanolamin grubundan sedatif ve antikolinerjik etkileri olan bir antihistaminiktir. Genellikle uyku bozukluðu tedavisinde kullanýlan kýsa etkili bir ilaçtýr. Tek baþýna kullanýlabildiði gibi soðuk algýnlýðý için kullanýlan ilaçlarla da kombine halde bulunabilmektedir. Literatürde tek baþýna doksilamin süksinat intoksikasyonu ile ilgili az sayýda yayýn bulunmakta ve bun...
متن کاملMaternal safety of the delayed-release doxylamine and pyridoxine combination for nausea and vomiting of pregnancy; a randomized placebo controlled trial
BACKGROUND Nausea and vomiting of pregnancy (NVP) is the most common medical condition in pregnancy, affecting up to 80% of expecting mothers. In April 2013 the FDA approved the delayed release combination of doxylamine succinate and -pyridoxine hydrochloride (Diclegis®) for NVP, following a phase 3 randomized trial in pregnant women. The fetal safety of this medication has been proven by numer...
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ژورنال
عنوان ژورنال: Hospital Pharmacy
سال: 2013
ISSN: 0018-5787,1945-1253
DOI: 10.1310/hpj4809-762